Contraceptive advice for patients who have received Sugammadex

Version 1  |  Updated 09th April 2026
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Contraceptive Advice for Patients Who Have Received Sugammadex

Patient Information

Anaesthetics Department

  • Author ID:           ME / NP
  • Leaflet Ref:         Ana 007
  • Version:              1
  • Leaflet title:         Contraceptive advice for patients who have received Sugammadex
  • Date Produced:   September 2024
  • Expiry Date:        September 2026
 

Introduction. 

As part of the general anaesthetic you have received, you have been administered a drug to relax your muscles. 

Before you were woken up, we administered another drug (reversal drug) to reverse this effect. You have been given a reversal drug today called Sugammadex. 

Sugammadex temporarily increases your likelihood of becoming pregnant after unprotected sexual intercourse in certain situations.

 

 

What should you do if you are using an oral hormonal contraceptive tablet/ pill?

Types of oral hormonal contraceptive you may be using: 

  • Progesterone only contraceptive ‘Mini Pill’ 
  • Combined oral contraceptive ‘Pill’ 

The effect of Sugammadex means that even if you took your pill this morning, it is the equivalent to one missed pill

Advice:

You must follow the missed pill advice in the package leaflet of the oral contraceptive.

 

 

 

What should you do if you are using any other type of hormonal contraceptive?

Other types of hormonal contraceptive you may be using: 

  • Contraceptive implant eg: Etonogestrel (Nexplanon®)
  • Hormonal Intra-Uterine System (IUS) eg: Levonorgestrel (Mirena®), Jaydess®, Levosert®, Kyleena®
  • The contraceptive injection eg: Medroxyprogesterone (Depo-Provera), SAYANA® PRESS, Noristerat®
  • The contraceptive patch (EVRA 203)

 

Advice:

You must use a barrier method of contraceptive e.g., condoms for the next seven days.

 

 

 

 

What should you do if you are using any non-hormonal contraceptive?

Types of non-hormonal contraceptive you may be using: 

  • Condoms
  • Cervical caps
  • Diaphragm
  • Contraceptive sponge
  • Copper IUD
  • Spermicide

 

Advice:

No further action is required. Sugammadex only reduces the effectiveness of hormone-based contraceptives.

 

 

Frequently asked questions

Will other drugs given to me as part of the anaesthetic affect my hormonal contraceptive?

No, this interaction is not known to occur with other anaesthetic-related drugs. 

 

Where can I get more information?

For further contraceptive advice please contact your GP or local sexual health and contraceptive services. 

Wrightington, Wigan & Leigh NHS Trust cannot accept responsibility for information provided by other organisations. 

 

Acknowledgement

This leaflet was  developed based on the original leaflet designed by by Dr Neha N Passi, ST4 Anaesthetic Registrar, Whipps Cross Hospital.

Last modified 09th April 2026 14:25:41 pm